The Aloe Vera plant Uses has been used as a cure and a healing agent for hundreds of years. There are many benefits that go along with Aloe Vera care and if you know what it can be used for you can experience some of these benefits.
It is an herb that is very popular and has been used as an additive in bath products, lotions, gels, and much more.
Aloe Vera plant Uses for Different Categories:
You can find aloe vera in many different forms and it can be used on your skin and internally to help with condition like:
Healing wounds. Aloe vera gel is an natural effective product to apply to wounds or our body for massage or to help them heal better.
Lower cholesterol and triglycerides.
Reduce blood pressure.
Improve dental health.
Treat ulcerative colitis.
Relieve symptoms of psoriasis.
Aloe Vera plant Uses for massage.
It is also known as one of the most effective natural treatments for acid reflux, which over 75% of the United States population suffers from.
If you want to grow your own aloe vera plant at home you need a few tips to help you with the care of this plant.
Aloe Vera Care Tip 1:
First, it is not hard to care for this African plant and it will do very well in sand soil. You want to make sure the soil is drained well and you want to actually let the soil dry out in between waterings.
This is a succulent plant and it does not have to be watered every single day like some plants require. Since the plant stores the water in its’ leaves over watering can cause the plant to actually start to rot.
Aloe Vera Care Tip 2:
Second, you will need to make sure you water the plant differently in each season. It will not require as much water during the winter months, but when it comes to the summer you will need to water your aloe vera plant much more often.
When you are trying to follow proper aloe vera care you also want to make sure you are not using tap water for the plan. Distilled water or even a light compost tea is much better than any water that will contain chlorine. The chlorinated tap water can cause the plant to brown over time.
Aloe Vera Care Tip 3:
Last, when practicing proper aloe vera care you want to make sure the plant is not in any harsh sunlight. If it is over exposed to the sun the leaves will become brown. You want to make sure the plant gets sunlight, but it should be indirect and not direct sunlight.
You also want to make sure you protect the plant in the winter from frost by bringing it inside or covering it during any days that could be cold enough for frost.
If you use these three tips and you are very careful about the aloe vera care you provide you will find that the aloe plant can be one of your favorite houseplants.
You can use it for the health benefits without having to spend a large amount of money in stores to get the commercialized versions of Aloe Vera.
Plus when you keep your aloe plant inside it will help to improve the quality of your aid by filtering out many of the harmful pollutants that are found in homes.
Their is many aloe vera plant uses benefits for human body because its natural cure clean with side effect and give you much more better results.
If you want to make sure you are getting the full benefits of the Aloe Vera plant you need to understand the uses that you can from the Uses for Aloe Vera Juice and from the gel.
The most common usage for Aloe Vera is for skin care, but there are many other benefits you can get from both the juice and the gel. Here are the two main uses for the Aloe Vera juice and some of the other benefits you can get from this amazing plant.
First Uses of Aloe Vera:
Uses for Aloe Vera Juice for Stomach Ache:
The first Uses for Aloe Vera Juice of the Aloe Vera plant is to help you cure pretty much any minor stomach and intestinal problems. This includes minor stomach aches and constipation aloe vera good work on it.
Aloe Vera juice is found in many of the top colon cleanse products and it works very well as a laxative. If you have a stomach ache or if you are backed up you can drink the juice twice a day to help cure your issue, in a natural way.
Second Uses of Aloe Vera:
Uses for Aloe Vera Juice on Acid Reflux:
The second major Uses for Aloe Vera Juice is to help cure acid reflux. This is a very common problem for many adults and if you want a good natural cure for your heartburn you can use Aloe Vera. It is recommended that you drink the juice at least twice a day to help build up an immunity to this horrible burning disease.
Aloe Vera Gel Cure HIV or Cancer:
There are many other uses for the juice of the Aloe plant and you can use it to cure many internal issues. It has not been proven to help cure HIV or cancer, but many believe it can help to lessen the pain and the effect of these diseases. The Aloe Vera plant has been involved in many medicines for centuries and is a healing plant that can be used for many things.
Aloe Vera Gel For Sunburn:
You can also use Aloe Vera in a gel form for sunburns, other minor burns, cuts, scrapes, and to help keep your skin soft. Many will also use it to help treat Eczema and many other skin issues. The great thing is that Aloe Vera is available in more than one form and you can actually grow the plant in your home as well.
If you are looking to purchase Aloe Vera juice you can find it online and you can also find it in many health food stores. If you cannot find the juice form you can also get
Aloe Vera in a powder form, which can be mixed in with another juice or with tea. The other option is to grow the plant at home, which can help you use it for many of the benefits if you take the time to learn to care for your Aloe Vera plant properly.
Regardless of the reason that you want to use Aloe Vera it is a very natural cure that you can take advantage of for many things. There are quite a few people that believe it is a cure-all that can help the body heal faster and help to build up the immune system. Aloe Vera juice does contain vitamin C, B12, and E, which are essential to living a healthy life as well.
Are you suffering from digestive disorders? Looking for Aloe Vera Gel Uses and Benefits, but don’t know where to start?
Do you know why Aloe Vera Gel And your Digestive Tract are related? Research shows that by regularly using Aloe Vera Gel, you can eliminate many of your digestive tract issues.
Digestive tract issues are painful and very uncomfortable to experience, by applying Aloe Vera Gel you can reduce your pain as it helps in cleaning the body internally and ensures that you are not constipated. The gel ensures that whatever we consume, is digestive completely.
The Aloe Vera Gel also helps relives the painful symptoms that you may face due to problems in the digestive tract. Therefore, log on now and cure your digestive tract issues with the Aloe Vera Gel.
13.Aloe Vera Gel Uses and Benefits For Your Circulatory System- Why Use It?
Aloe Vera has been known to be the best cure for every issue that you may have. Therefore, you must have noticed how everyone always keeps suggesting it to you, whenever you have an issue. Well, it has been scientifically proven that using Aloe Vera gel can have many positive impacts on your body, in this article; we see how Aloe Vera gel is beneficial for your circulatory system.
Aloe Vera gel can be used for many health related issues, including improvement of your circulatory system. aloe vera plant uses that has the ability to remove any sort of toxins in your body.
By removing the toxins, it ensures that your body is absorbing the safe and clean blood. Moreover, the application of the gel will ensure that blood is circulating to every part of your body.
You will only be required to apply the gel once a day. With consistent use, you will surely see an improvement with Aloe Vera gel for your circulatory system. By using Aloe Vera gel for your circulatory system, you will not need to opt for any other harsh medicines, as this will keep you fit.
12.Aloe Vera Gel Healing All Your Wounds!
Aloe Vera Gel is present in sufficient amounts in the leaves of this amazing plant. It is filled with numerable nutrients, approximately 75 with huge amounts of water that is the most beneficial component, which our body requires.
Due to its antiseptic quality, when our wounds are treated with this gel, it leaves a very appropriate mild anesthetic feeling, relieving us from all the pain, discomfort and itching. It boosts up blood circulation and increases the rate of blood flow to the affected areas and results in the stimulation of all the skin cells, which are responsible to heal our wounds.
Aloe Vera Gel, being the most amazing and natural wound healing remedy, is also considered a cooling tonic. It is anti-fungal and purgative herb which when treated cures our wounds dramatically. The production of scar tissues gets restricted and all its soothing components treat our wounds.
Bacterial contamination is stopped as Aloe Vera Gel is anti-bacterial and stops further worsening of the wound and skin infections. It soothes the burning sensation quickly and heals in approximately 12 days with no after effects. Due to a sufficient amount of amino acids present, it becomes the best healing plant that heals all wounds!
11.Aloe Vera Gel Surely Cleanses Your Body!
Aloe Vera cannot stop itself from giving us all the possible health benefits and treat every health issue of millions of people. Aloe Vera Gel has also proved to be the most effective body and colon-cleansing product as reported by the world’s renowned dermatologists and doctors. With the help of this natural ingredient, it cleans your body.
It removes all the toxic substances present with the help of some components present in this Aloe Vera Gel, which is saponin, proteolytic, and lignin. Gastro Intestinal tract is cleansed with the help of saponin, which acts like a detergent.
Inside your bowel, all the rotten waste present can be digested with the help of enzymes present in Proteolytic. Layers of skin our penetrated with the help of the third component present in the gel, Lignin.
Our human bodies need cleaning to prevent it from getting all the diseases and viral infections. All the harmful and contagious substances are cleansed, making your immune system healthy and free from any toxins.
As our intestinal tract gets clean, it boosts all our energy levels, which in all encourages our overall health. Aloe Vera Gel is seen as an ancient healer and keeps your body clean and healthy.
10.Beautiful Clear Skin with Aloe Vera Gel!
Acne is a problem faced by many teenagers especially, nowadays. Although it does not threaten our life or considered to be a harmful disease but it is something that ruins our self-esteem, and this feeling might end up in many serious problems. So yes, Acne is not a small issue.
Many individuals roam around and search for many skin care products, wasting hundreds of dollars over these useless products. They don’t know that there are some remarkable natural products like Aloe Vera Gel that literally cure this problem in the most naturally, effective and affordable way. Dermatologists highly recommend Aloe Vera Gel due to its numerable acne healing properties.
Aloe Vera Gel, first removes acne from your skin, revitalizes it, improves it current condition, and then in the end prevents further breakouts and formation of pimples.
Healing process speeds up due to this gel as it regenerates skin and contain polysaccharides, which is the best skin-repairing agent, naturally present in Aloe Vera. Swelling of pimples can also be cured due to numerous vitamins present in Aloe Vera. Just regain the moisture, soften your skin like never before, and get a clear, fresh and smooth skin to dazzle everyone out there.
9.Bronchitis Cured- Thanks to Aloe Vera Gel!
Doctors define bronchitis as the inflammation of air tubes that are responsible to give air to our lungs. Such a disease results in swelling, mucus and reddening, leading to extreme pain and discomfort.
There are usually two types of Bronchitis, one is a viral infection and happens when you encounter the problem of sore throat. The other is caused by smoke or tobacco and thus leading to the production of mucus, coughing and has a long-term effect, damaging lungs permanently.
Aloe Vera Gel is a natural and nutrition supplement that actually stops Bronchitis to ruin your life more and make things worse for you. This herbal treatment heals your Bronchitis with an Ayurveda cure.
This gel easily clear up your lungs and stop the further production of mucus. Our immune system get strengthen and free us from all the pain and drowsiness. The problem of severe sore throat is cured and naturally stops all viruses to attack us.
With the Aloe Vera Gel, the problems of wheezing and shortness of breath can be cured. Inflammation is cured with the anthraquinones present in Aloe Vera and all lung infections and allergies are treated due to magnesium present in Aloe Vera. So, make a sensible and wise decision and get this gel before it is too late.
8.Cure Rheumatoid Arthritis with Aloe Vera Gel!
Rheumatoid Arthritis creates several problems for you, mobility issues being on the top. It lowers the quality of life and gives you extreme pain and unbearable discomfort. Inflammation of joint, tenderness in the joints, persistent joint pains, weight loss and extreme weakness are one of the symptoms of this arthritis.
Doctors often treat this arthritis by giving you a bag of antibiotics and various expensive medicines but trust me, the more sensible and wise way to fight this pain is to adopt some natural ways such as Aloe Vera Gel, which give the best possible results in a short time period.
One thing, which Aloe Vera Gel does and antibiotics do not, is that it contains a repairing agent for the damaged tissues. These artificial medicines often end up giving the patient a number of side effects but this does not happen when it comes to this natural effective plant that repairs and regenerated cells and tissues in your body.
The problem of swollen joints can easily be cured as Aloe Vera Gel has all the anti-inflammatory properties. This gel is applied on the affected joints and cures this debilitating disease in a short span of time.
7.Grab All The Health Benefits with Aloe Vera Gel! Aloe Vera Gel health Benefits:
Aloe Vera is a natural herb which contains an extensive amount of vitamins, amino acids and minerals which makes the best natural product one can have to maintain general health.
Aloe Vera should be made a part of daily diet. Aloe Vera strengthens the edifice of our health by giving us possible health benefits and treats every internal and external body part. First of all, Aloe Vera is seen as a great natural skin care product.
One can easily get and maintain their healthy looking and radiant skin with the help of Aloe Vera Gel. It is good skin healing agent that gives the best treatment of all skin problems.
Secondly, our immune system gets strong due to consumption of Aloe Vera. For optimum functioning, our body requires minerals, vitamins and various substances and this is what Aloe Vera Gel provides us.
Apart from these outer health problems, Aloe Vera treats your digestion and cleanses your stomach. Ingestion of this amazing natural herb cures all stomach problems. Joint and mobility flexibility can be easily gained due to Aloe Vera Gel being anti-inflammatory.
Daily intake of this plant boosts energy levels and cures all dental problems. Thus grab Aloe Vera Gel and see the BIG difference it has stored for you!
6.Heal your Digestion Problems with Aloe Vera Gel! Aloe Vera Gel For Digestion:
With an upset stomach, nothing looks good around you. In the upper abdomen, you feel the burning sensation along with a nauseate feeling and bloating in the stomach. This is the most disgusting feeling when you literally want to vomit when food comes in front of you. All these are symptoms of dyspepsia.
When it comes to Diarrhea, things get worse and unbearable. Mucus in the stools, together with constipation is the mostly encountered symptoms reported. You might end up going to a doctor for various medications to free you from the pain and the irritable condition
The best way to cure and heal your above digestion problems is to use Aloe Vera Gel. You might have not heard about it before, but trust me, it do wonders. It is considered the most effective supplement and aids you, easing your discomfort. It treats all the symptoms naturally with no harmful side effects.
It decreases the level of stomach acids and cures all digestion problems. Abdominal pain is usually due to Ulcerative Colitis, which results in inflammation, and this can be healed with the help of this gel. Therefore, Aloe Vera Gel is a good digestive aid and is the solution to all your digestion problems!
5.Oral Health with Aloe Vera Gel!
Aloe Vera Gel is something that treats everything. From digestion problems to lung problems, from skin problems to treating hair loss, it does miracles. Now, the list has added up another health benefit due to this ever-amazing gel and that is Oral Hygiene with the help of Aloe Vera.
Now, regularly Aloe Vera Gel Uses and Benefits is considered a very important natural ingredient in the toothpastes available in the market of various brands.
As Aloe Vera contains Vitamin B12, it treats Canker sore as this is caused by the deficiency of this specific vitamin. Aloe Vera Gel contains a myriad of very effective, natural and beneficial components that maintains and sustains oral health and hygiene.
Periodontal disease is now cured with the help of this gel as it contains a natural healing ingredient. Bacterial Contamination, which often leads to serious problems like inflammation of gums and mouth lesions, is treated with this magical natural herb.
Due to its laxative and antiseptic quality, it treats all dental problems such as gum diseases and even cracked lips. Studies and researches have shown some remarkable results, have reported Aloe Vera Gel to be the best solution to all your oral health issues, and is the best way out to get Oral Health.
4.Re-grow Your Hair with Aloe Vera Gel! Aloe Vera Gel For Hair Loss:
Hair loss is a problem which every individual is encountering these days, irrespective of what their age is. But with an increasing age, your hair follicles weaken and thus giving your severe hair issues. But now, you don’t have to worry about such a small problem, because Aloe Vera Gel is here to promote hair restoration in a completely natural way.
Once you get to know about the real cause behind your hair loss from your dermatologist, then you can surely go for this gel if it is able to treat that cause effectively.
Aloe Vera Gel restores hair due to enzyme that actually grows hair and makes them strong.
Due to Aloe Vera being a natural herb, it has no side effects and can be easily applied to the affected areas of your scalp. In case of a dried scalp, the natural properties of Aloe Vera revitalize your hair and bring them back to their natural condition.
Things can be made more convenient by mixing this gel with other natural products available in the market like coconut milk, so that it can be transformed into a kind of shampoo and applied easily to your scalps. Although, it works slowly, but this Aloe Vera Gel is worth it and do miracles, giving you long, healthy, shiny black hair.
3.Say Goodbye To Your Headaches:
Do you suffer from headaches every now and then? Can you not find a cure? If so, then you will be glad that you landed at this article. In this article, we give you a solution to those nasty headaches that just never seem to go away. So what is our secret? You can say goodbye to your headaches by using Aloe Vera.
The main reason people suffer from headaches is dehydration. By using Aloe Vera gel for headaches, you will rehydrate your skin. By rubbing the Aloe Vera gel for headaches, you will also improve your body’s circulation.
By improving the blood flow, you will also increase the amount of oxygen that your brain gets. Such effects will reduce the intensity of your headache at first and then you will notice that it is gone.
The Aloe Vera gel for headaches can be very effective when applied consistently. In addition, Aloe Vera gel can be used by anyone at anytime, as it does not contain any harsh chemicals.
Moreover, unlike other medication Aloe Vera gel for headaches is very affordable. Therefore, why should you opt for anything else then this natural effective cure?
2.Skin Care with Aloe Vera Gel! Skin Care Aloe Vera Gel:
how to use aloe vera gel on face,We know about all the amazing properties of Aloe Vera, and should not overlook the skin benefits it gives us naturally. It is the best skin care product better than all those branded and expensive products, which is a total money waste and leaves numerable side effects, as reported by able dermatologists.
From anti-ageing properties to treating various skin diseases and skin infections, Aloe Vera Gel is best for skin conditions. First, Aloe Vera Gel Uses and Benefits nourishes our skin tissues. As compared to water, Aloe Vera Gel is seen as a better skin-penetrating agent, delivering all the goodness and nutrients deep down.
Improve your skin complexions and get a healthy looking skin as Aloe Vera produces epidermal cells that tighten our skin, and thus leading to reduction in the production of wrinkles. This property of cell renewal and stimulation in the formation of collagen in our bodies makes it the best anti-ageing natural product.
1.Aloe Vera Gel Maintain pH Skin Balanced:
To counter all skin problems, maintaining the Ph. balance of our skin is mandatory and this is what Aloe Vera Gel do. Acne gets controlled and regeneration of skin becomes possible.
Lastly, when it comes to skin infections like psoriasis and eczema, Aloe Vera Gel treats everything and stops the worsening of these horrible skin diseases. So treat your skin and beautify if regularly Aloe Vera Gel Uses and Benefits.
The reason there are so many Benefits of the Aloe Vera Plant to be taken advantage of is because the plant itself is so medicinal. You might be surprised to know that not only can the plant be used on the skin but it can also be consumed for internal aloe vera medicinal uses benefits.
You simply peel open a leaf and scrape the gooey stuff from inside. From there it can be rubbed onto the skin like a salve or thrown into a smoothie for health reasons. No matter how you choose to use the plant, following you’ll find some of the most popular aloe vera benefits known to man.
Anti-fungal and Antibacterial Properties:
Benefits of the Aloe Vera Plant gel can help to naturally heal almost all fungus and parasites that you might come in to contact with. Because of its antibacterial properties, you can use aloe vera to help heal cuts and scrapes by keeping the area clean and free from infection.
Aloe vera is touted as a great burn relief because first, second, third and even fourth degree burns all tend to respond well to aloe vera. Simply apply fresh aloe vera gel onto the burn surface and let is sit for at least 20 minutes at a time until you see results. It’s pretty simple and also benefits of aloe vera drink.
By consuming the product, you can experience aloe vera benefits such as relief from inflammatory diseases such as arthritis. Aloe vera helps to soothe the tissues and organs of the body, relieving inflammation in the joints and muscles as well.
There is evidence that Benefits of the Aloe Vera Plant in the form of anti aging is very real. Aloe vera gel helps to keep the skin smooth and clear, and helps to get rid of wrinkles as well as prevent them. You will find that using aloe vera on the skin while at the same time consuming it on a regular basis will provide you with the best aloe vera benefits.
You can grow an aloe vera plant yourself and use the leaves right from the plant. You cna also purchase aloe vera drinks and other products that contain aloe vera at your local stores and health food shops.
You can also find aloe vera powder that is made from the leaves of the plant that is good as a supplement. You will also find that there are many products for the The reason there are so many aloe vera benefits to be taken advantage of is because the plant itself is so medicinal.
You might be surprised to know that not only can the plant be used on the skin but it can also be consumed for internal aloe vera benefits. You simply peel open a leaf and scrape the gooey stuff from inside. From there it can be rubbed onto the skin like a salve or thrown into a smoothie for health reasons.
No matter how you choose to use the plant, following you’ll find some of the most popular aloe vera benefits known to man.
The aloe vera plant has long been used by native cultures for its healing properties. They found what scientists are studying today about aloe vera benefits aloe vera tips for use both externally and internally.
Aloe vera can be applied topically to the skin as an anti-inflammatory, anti-bacterial, and anti-viral agent to help heal burns including sunburn and razor burn; scrapes and scratches; and rashes such as eczema and psoriasis; dry skin and dandruff; and even acne.
Another of the many aloe vera benefits aloe vera tips is that aloe vera is also available in juice, tablet, or pill form to take orally for treatment of internal epithelial tissue disorders.
The American Osteopathic Society has done studies that indicate aloe vera’s usefulness in treating stomach ulcers by signalling the body to release a gastric juice enzyme called pepsin that helps soothe stomach ulcers, colitis, and irritable bowel syndrome.
Another study found that aloe vera taken orally helped alleviate asthma symptoms in the lungs and nasal sinuses by reducing inflammation in the tissues and possibly by boosting the immune system.
More important aloe vera benefits aloe vera tips are studies on aloe’s ability to raise the white blood cell count in people with low immunity, such as colds and other viruses. The US Food and Drug Administration approved the use of aloe vera for treating HIV in 1994.
Scientists are also studying to learn its effects on certain cancers like leukemia and tumors. People who use aloe vera report that the plant has eased all kinds of conditions such as heartburn, indigestion, insomnia, leg cramps, vaginitis, hemorrhoids, bladder infections, kidney infections, diverticulitis, constipation, and that its anti-inflammatory properties help them with the swollen joints of arthritis its also aloe vera benefits for skin.
One of the interesting facts about aloe vera is that it is the only vegetarian source known to contain vitamin B12. It has other vitamins and minerals including amino acids, calcium, enzymes, essential fatty acids, germanium, magnesium, protein, zinc, vitamin A, vitamin E, and vitamin C.
Benefits of the Aloe Vera Plant is 99 percent water, so all these powerful ingredients are in just one percent of this useful plant. Although rare, it’s possible to have an allergic reaction to aloe vera and for more details.
A few aloe vera benefits aloe vera tips are before using it topically, test it on a tiny patch of skin first, and discuss it first with a medical professional before taking it internally, especially women who are pregnant or breast feeding because aloe vera side effects.
The research was undertaken in three parts: A literature review of the composition and actions of Benefits of Aloe Vera; Laboratory work with cell cultures; A pilot study using aloe vera for the treatment of chronic venous leg ulcers.
Benefits of Aloe Vera for Leg Ulcers:
Benefits of Aloe Vera appears to speed up the healing of damaged epithelial tissue in burns and leg ulcers by providing essential micronutrients, an anti-inflammatory effect, an antimicrobial effedct and through the stimulation of skin fibroblasts.
In the case of the pilot study carried out on chronic venous leg ulcers, seven patients were selected by nursing staff as being suitable for study. These patients had leg ulcers which had failed to heal using conventional methods including skin grafting its so much good Benefits of Aloe Vera on wound problems.
The ulcer was then traced, photographed an swabbed, and blood taken for routine testing. Each patient was given an 60 ml (4 fl oz) each day of aloe vera gel drink consisting of 98% stabilised aloe vera gel.
The ulcer crater was irrigated with tap water to remove debris. The crater was then filled with topical aloe jelly preparation containing 86 % stabilised gel. This process was implemented daily if possible either in the department or by trained nursing help in the community.
Seven ulcers were treated which ranged in age from 4 to 15 years. Six ulcers were venous leg ulcers and in one patient with systemic lupus erythematmosis (SLE). The patient sample included six females and one male.
Six patients found the regime very acceptable and pleased with the cleansing effect of aloe which resulted in reduced exudate and odour and less seepage through the bandaging. One older patient withdrew from the study due to the initial stinging sensation when the aloe jelly is first applied and aloe vera for infections good working on it.
This common effect passes off in 20-30 minutes. The results indicate that subsequent swabs destroyed the wound’s infecting bacteria, predominantly pseudomonas. Three of the six wounds healed completely, one partially and one evidenced no improvement.
No attempt was made to distinguish the internal effects of the Benefits of Aloe Vera drinking gel from the effects of the topical aloe gel preparation. A pleasant side effect of the treatment was a clear change in the quality of the patients’ hair, nails and skin.
Although no definitive conclusions can be drawn from such a small pilot study, the results are promising and indicate the need for a larger trial. Ethical permission has been received to carry out a randomised control trial involving 30 patients which will compare the topical aloe gel effects with standard gel dressing.
Subsequent to the publication of this article, Dr Atherton reported that the patient with SLE experienced complete healing and the patient who had the very severe ulcer for 15 years was healed to the point where a skin graft was possible. Such results are highly significant bearing in mind that all previous treatments had failed over many years.